Pharmacokinetic Modeling

Information to Better Understand the Behavior of Chemicals in the Body

CTEH has years of experience conducting pharmacokinetic modeling to assess how drugs and other chemicals are absorbed, distributed, metabolized, and eliminated from the bodies of humans and animals. We offer both traditional and physiologically-based pharmacokinetic (PBPK) modeling.

Our toxicologists are experienced in developing and applying traditional and PBPK modeling to assess a wide range of effects. This includes reconstructing exposure & dose, supporting the establishment of health-based guidelines, assessing the variability of chemical behavior across large populations, and improving dose-response characterizations for assessments of chemical exposures. Our mission is to help clients increase product safety, and better prevent and prepare for chemical exposures.